Nanocapsule’s Components Can Kill Antibiotic-Resistant Bacteria

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The resistance of bacteria against antibiotics is one of the pressing problems the world faces today. Many types of bacteria have learned to adapt in protecting themselves against drugs. Unfortunately, this is the case even when the drugs are designed to kill bacteria.

A team of German and English scientists conducted a study to learn how organic plant compounds can fight antibiotic-resistant bacteria.

The University of Leeds, University of Münster, and the University of Erlangen-Nuremberg conducted the study. The results are published in ACS Applied Bio Materials journal.

The Dangers of Helicobacter Pylori

Helicobacter pylori is a perfect example of a pathogen that is antibiotic resistant. Despite being harmless, this type of bacteria can cause ulcers, which can later lead to stomach cancer.

Based on the current data, helicobacter pylori are found across 4.4 billion people all over the world. It is common in Africa, Latin America and Caribbean.

The Centers for Disease Control and Prevention (CDC) stated that antibiotic resistance happens when bacteria have the power to beat the drugs made to kill them.  

The World Health Organization WHO) declared that helicobacter pylori are antibiotic-resistant and can cause damage to human health.

Components That Reduce Inflammation and Infection

The researchers discovered that capsules loaded with curcumin are effective in killing H. Pylori. Curcumin, usually found in turmeric, is known to have anti-inflammatory properties.

The researchers added that the nanocapsules act to cover the bacteria with a coating. The coating prevents the bacteria from binding to the cells in the stomach.

Moreover, researchers noted that the curcumin in the nanocapsules isn’t just the key. Nanocapsules also have lysozyme, an enzyme that can reduce bacterial infection.

The Future of Antimicrobial Resistance

Francisco Goycoolea, co-author of the study and professor at the School of Food Science and Nutrition at Leeds, said that medical experts recognized antimicrobial resistance as one of their struggles. If no action takes place to overcome it, a higher number of deaths can arise in 2050.

As mentioned by Andreas Hensel, a professor at the Institute for Pharmaceutical Biology and Phytochemistry of the University of Münster and a co-author of the said study, antibiotics have broad compounds. These antibiotics commonly used contain these compounds that can destroy the cell walls and membrane.

Hensel added that customizing antibiotics is essential. Doing so ensures that the bacteria don’t get resistant to antibiotics.

Experts all agree that diseases caused by antibiotic-resistant germs are difficult to cure. People carrying these pathogens stay longer in hospitals and even get more expensive treatments.

With this recent discovery, fighting bacteria will be remarkably effective with newly-formulated nanocapsules that contain natural ingredients.

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